Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents

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Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents

BACKGROUND Cardiovascular diseases are the most prevalent cause of morbidity and mortality affecting millions of people globally. The most effective way to counter cardiovascular complications is early diagnosis and the safest non-invasive diagnostic approach is magnetic resonance imaging (MRI). In this study, superparamagnetic ferrite nanoparticles doped with zinc, exhibiting highly enhanced s...

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Synthesis and Characterization of Chitosan Coated Manganese Zinc Ferrite Nanoparticles as MRI Contrast Agents

Manganese zinc ferrite nanoparticles (MZF NPs) were synthesized by using a direct, efficient and environmental friendly hydrothermal method. To improve the colloidal stability of MZF NPs for biomedical applications, NPs were coated with chitosan by ionic gelation technique using sodium tripolyphosphate (TPP) as crosslinker. The synthesized NPs were characterized by X ray diffraction (XRD) analy...

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Magnetic resonance imaging (MRI) is a powerful clinical imaging technique for the non-invasive diagnosis and posttherapy assessment of a variety of diseases. MRI contrast can be enhanced by the use of positive or negative contrast agents resulting in brighter (T1-weighted) or darker (T2-weighted) images, respectively. Superparamagnetic iron oxide (SPIO) nanoparticles are T2 contrast agents that...

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synthesis and characterization of chitosan coated manganese zinc ferrite nanoparticles as mri contrast agents

manganese zinc ferrite nanoparticles (mzf nps) were synthesized by using a direct, efficient and environmental friendly hydrothermal method. to improve the colloidal stability of mzf nps for biomedical applications, nps were coated with chitosan by ionic gelation technique using sodium tripolyphosphate (tpp) as crosslinker. the synthesized nps were characterized by x ray diffraction (xrd) analy...

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ژورنال

عنوان ژورنال: Journal of Nanobiotechnology

سال: 2016

ISSN: 1477-3155

DOI: 10.1186/s12951-016-0157-1